Tanshinone IIA | AP-1 transcription factor inhibitor
NMR (Conforms)
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Probucol (23288-49-5) is a unique antilipidemic drug which inhibits the oxidation of LDL cholesterol preventing the genesis of macrophage-derived foam cells and thus suppressing the formation
CBL0137 (1197996-80-7) is an anticancer agent that activates p53 and suppresses NF-kB via trapping of the FACT (facilitates chromatin transcription) complex, an important histone chaperone that mediates nucleosome
Vaccine adjuvants are materials that enhance the magnitude and duration of protective immune responses, typically via pattern recognition receptors (PRR). 2E151 (2416963-37-4) is a co-adjuvant that
alpha-Lipoic acid (1077-28-7) is an endogenous antioxidant.1,2 Treatment with alpha-lipoic acid increased hepatic nuclear Nrf2 levels, induced Nrf2-mediated gene transcription, and reversed age-related decline in hepatic
Probucol (23288-49-5) is a unique antilipidemic drug which inhibits the oxidation of LDL cholesterol preventing the genesis of macrophage-derived foam cells and thus suppressing the formation
CBR-470-1 (2416095-06-0) is an activator of NRF2 signaling (EC50 ~ 1 µM cellular ARE-LUC assay).1 It inhibits phosphoglycerate kinase 1 leading to a build-up of methylglyoxal which inactivates
SR1078 (1246525-60-9) is an agonist of the orphan nuclear receptors RORα and RORγ.1 It attenuated intrapancreatic pathological changes in mouse models of chronic pancreatitis via restoration of the circadian
Isothiocyanate constituents of cruciferous vegetables are potent chemopreventive agents for carcinogen-induced cancers in rodents.1 Phenylhexyl isothiocyanate (PHITC; CAS 133920-06-6) was the most potent in a series
CBL0137 (1197996-80-7) is an anticancer agent that activates p53 and suppresses NF-kB via trapping of the FACT (facilitates chromatin transcription) complex, an important histone chaperone that mediates nucleosome
Verrucarin A (3148-09-2) is a macrocyclic trichothecene mycotoxin from Myrothecium sp. It is a potent and selective inhibitor of the steroid receptor coactivator-3 and selectively down-regulates its
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4-Methylbenzyl-N-bis[daunomycin], mesylate salt
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