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  • Focus Biomolecules cell signaling reagent supplier, chemical structure of DBeQ | p97 inhibitor | CAS 177355-84-9
    $65.00
    DBeQ (177355-84-9) is a potent, selective and reversible inhibitor of the AAA-ATPase p97 (ATPase associated with diverse cellular activities). Ki=3.2 μM. DBeQ blocks ubiquitin-dependent protein clearance pathways. Cell...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of MDBN | p97 inhibitor | CAS 1485-00-3
    $40.00
    MDBN (1485-00-3) is an irreversible inhibitor of p97 (IC50 < 10 μM). Cell permeable References/Citations1) Chou et al. (2011), Quantitative cell-based protein degradation assays to identify and classify drugs that...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of NSC-632839 | DUB inhibitor | CAS 157654-67-6
    $65.00
    NSC-632839 (157654-67-6) is a pan-specific ubiquitin isopeptidase inhibitor. (IC50= 45, 37 and 9.8 μM for USP2, USP7 and SENP2 respectively) Does not effect proteasome proteolytic activity. NSC-632839 induces apoptosis...

  • Focus Biomolecules supplier, chemical structure of NSC-697923 | Ubiquitin E2 Conjugating enzyme inhibitor | CAS 343351-67-7
    $50.00
    NSC-69723 (343351-67-7) is a selective inhibitor of E2 ubiquitin-conjugating enzyme, Ubc13-Uev1A. Does not inhibit UbcH5c activity. Impedes the formation of the Ubc13 and inhibits NF-κB activation in activated B...

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