Pyroptosis

  • 1G244 | DPP8/9 inhibitor

    CAS:
    847928-32-9
    Catalog Number:
    10-4584
    Activity:
    DPP8/9 inhibitor
    Chemical Names:
    (S)-2-Amino-4-{4-[bis-(4-fluorophenyl)-methyl]piperazin-1-yl}-1-(1,3-dihydro-isoindol-2-yl)-butane-1,4-dione
    Alternate Name:
    PTX-1210
    Molecular Weight:
    504.57
    Molecular Formula:
    C29H30F2N4O2
    Solubility:
    Soluble in DMSO (>20 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $70.00
  • Belnacasan | ICE/caspase-1 inhibitor

    CAS:
    273404-37-8
    Catalog Number:
    10-4399
    Activity:
    ICE/caspase-1 inhibitor
    Chemical Names:
    (S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; VX-765
    Molecular Weight:
    508.99
    Molecular Formula:
    C24H33ClN4O6
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white to white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
  • Talabostat mesylate | Pyroptosis inducer / Inflammasome activator

    CAS:
    150080-09-4
    Catalog Number:
    10-4005
    Activity:
    Pyroptosis inducer / Inflammasome activator
    Chemical Name:
    ((2R)-1-((2S)-2-Amino-3-methylbutanoyl)pyrrolidin-2-yl)boronic acid methanesulfonate
    Alternate Names:
    Val-boroPro; PT-100
    Molecular Weight:
    310.18
    Molecular Formula:
    C9H19BN2O3 • CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00