REV-ERB and muscle regeneration
FOCUS on muscle regeneration. A group at Wash. U. recently reported on a compound designated BE2012 in J. Med. Chem. BE2012 was shown to be a
FOCUS on muscle regeneration. A group at Wash. U. recently reported on a compound designated BE2012 in J. Med. Chem. BE2012 was shown to be a
In a paper just out in Redox Biology, the authors show that inhibition of 15-OH-PGDH with SW033291 restores redox homeostasis and confers neuroprotection in Parkinson’s disease.
Focus Biomolecules will be exhibiting at the annual meeting of the International Society for Stem Cell Research in Montreal, July 8 – 10. Stop by our
FOCUS on Drug Repurposing. Montelukast is a cysteinyl leukotriene receptor (CysLTR1) antagonist currently in use for asthma. In a paper just out in Nature Cancer, a
FOCUS on PROTACs. On May 1st the first PROTAC, a heterobifunctional protein degrader and a new therapeutic modality, was approved by the FDA. Vepdegestrant (Arvinas’ Veppanu)
FOCUS on Pancreatic Cancer. In a paper just out in Nature Medicine, the team at Actuate Therapeutics reported the results of their Phase II trial on
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