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Conduritol B epoxide | Glycosidase inhibitor

CAS:
6090-95-5
Catalog Number:
10-1172
Activity:
β-Glycosidase inhibitor
Alternate Names:
CBE
Chemical Name:
D,L-1,2-Anhydro-myo-inositol
Molecular Weight:
162.14
Molecular Formula:
C6H10O5
Solubility:
Soluble in Water (up to 25 mg/ml) or in DMSO
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Compound is hygroscopic, protect from moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Conduritol B epoxide (6090-95-5) is a β-Glycosidase inhibitor.1,2 May be used for generation of the “Gaucher mouse”3 and the in vitro model of the Gaucher cell4.

References/Citations:

1) Datta and Radin (1988), Normalization of liver glucosylceramide levels in the “Gaucher” mouse by phosphatidylserine injection;  Biochem. Biophys. Res. Commun., 152 155
2) Radin and Vunnam (1981), Inhibitors of cerebroside metabolism;  Methods Enzymol., 72 673
3) Stephens et al. (1981), Distribution of conduritol B epoxide in the animal model for gaucher’s disease (Gaucher mouse); Biochim. Biophys. Acta, 672 29
4) Newburg et al. (1986), beta-Glucosidase inhibition in murine peritoneal macrophages by conduritol-B-epoxide: an in vitro model of the Gaucher cell;  Biochim. Biophys. Acta, 877 121

Conduritol B epoxide | Glycosidase inhibitor is also available in the Cellular Metabolism Library.
CAS:
6090-95-5
Catalog Number:
10-1172
Activity:
β-Glycosidase inhibitor
Alternate Names:
CBE
Chemical Name:
D,L-1,2-Anhydro-myo-inositol
Molecular Weight:
162.14
Molecular Formula:
C6H10O5
Solubility:
Soluble in Water (up to 25 mg/ml) or in DMSO
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Compound is hygroscopic, protect from moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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