Caspases
-
Belnacasan | ICE/caspase-1 inhibitor
From $45.00CAS:273404-37-8Catalog Number:10-4399Activity:ICE/caspase-1 inhibitorChemical Names:(S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; VX-765Molecular Weight:508.99Molecular Formula:C24H33ClN4O6Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white to white solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Emricasan | pan-Caspase inhibitor
From $70.00CAS:254750-02-2Catalog Number:10-4280Activity:pan-Caspase inhibitorChemical Names:(3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acidAlternate Name:IDN-6556; PF-03491390Molecular Weight:569.51Molecular Formula:C26H27F4N3O7Solubility:Soluble in DMSO (20 mg/ml)Physical Properties:White solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
PAC-1 | Procaspase activator
From $30.00CAS:315183-21-2Catalog Number:10-2979Activity:Procaspase activatorChemical Name:4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]-methylene]hydrazideMolecular Weight:392.49Molecular Formula:C23H28N4O2Solubility:Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 15 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol must be stored under inert gas at -80°C and will be stable for up to 2 months.Shipping Code:RT -
Q-VD-OPh | Pan-specific caspase inhibitor
From $80.00CAS:1135695-98-5Catalog Number:10-2940Activity:Pan-specific caspase inhibitorChemical Name:Quinolyl-valyl-aspartyl-[2,6-difluorophenoxy]methyl ketoneMolecular Weight:513.49Molecular Formula:C26H25F2N3O6Solubility:Soluble in DMSO (up to 15 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
SM-164 | Smac mimetic
From $190.00CAS:957135-43-2Catalog Number:10-5464Activity:Smac mimeticChemical Names:(3S,3′S,6S,6′S,10aS,10′aS)-N,N′-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamideMolecular Weight:1121.45Molecular Formula:C62H84N14O6Solubility:Soluble in DMSO (50 mg/ml)Physical Properties:White to pale-yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
1
2
