TGF
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Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic
From $45.00CAS:700874-72-2Catalog Number:10-4110Activity:Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeuticChemical Name:4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamideAlternate Names:LY2157299Molecular Weight:369.43Molecular Formula:C22H19N5OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
GW788388 | TGF-ß receptor kinase inhibitor
From $80.00CAS:452342-67-5Catalog Number:10-5521Activity:TGF-ß receptor kinase inhibitorChemical Names:4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamideMolecular Weight:425.49Molecular Formula:C25H23N5O2Solubility:Soluble in DMSO (18 mg/ml with warming)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
IDE1 | Inducer of Definitive Endoderm
From $80.00IDE1 (1160927-48-9) induces robust differentiation of embryonic stem cells into endoderm (EC50 = 125 nM) in both mouse and human cells via activation of the TGFß signaling pathway.1,2 It has […]
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IDE2 | Inducer of Definitive Endoderm
From $80.00IDE2 (1136466-93-7) induces robust differentiation of embryonic stem cells into endoderm (EC50 = 223 nM) in both mouse and human cells via activation of the TGFß signaling pathway.1 It was […]
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LY-364947 | ALK5 inhibitor
From $75.00CAS:396129-53-6Catalog Number:10-1492Activity:ALK5 inhibitorAlternate Names:HTS-466284Chemical Name:4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinoloneMolecular Weight:272.31Molecular Formula:C17H12N4Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Brown solidPurity:98% by TLCStorage Temperature:RT (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
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