Mitochondrial Transporters

  • Bongkrekic Acid | Inhibits MPT pore opening

    CAS:
    11076-19-0
    Catalog Number:
    10-2751
    Activity:
    Inhibits MPT pore opening
    Chemical Name:
    3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic acid
    Molecular Weight:
    486.61
    Molecular Formula:
    C28H38O7
    Solubility:
    Miscible with DMSO.
    Physical Properties:
    Solution at 1 mg/mL (2 mM) in 0.01M Tris buffer pH 7.5 (contains 1 mg net bongkrekic acid per mL)
    Purity:
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    Blue Ice
    From $160.00
  • CGP-37157 | MPTP inhibitor

    CAS:
    75450-34-9
    Catalog Number:
    10-4250
    Activity:
    MPTP inhibitor
    Chemical Name:
    7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one
    Molecular Weight:
    324.22
    Molecular Formula:
    C15H11Cl2NOS
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solution in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
  • KB-R7943 mesylate | NCX inhibitor

    CAS:
    182004-65-5
    Catalog Number:
    10-1163
    Activity:
    TRPC channel blocker
    Chemical Name:
    2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate
    Molecular Weight:
    427.49
    Molecular Formula:
    C16H17N3O3S CH3SO3H
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
  • Lonidamine | Inhibits Cancer Cell Metabolism

    CAS:
    50264-69-2
    Catalog Number:
    10-4563
    Activity:
    Decreases aerobic and anaerobic glycolysis in tumor cells
    Alternate Names:
    AF1890; Diclondazolic acid
    Chemical Name:
    1-[(2,4-Dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
    Molecular Weight:
    321.16
    Molecular Formula:
    C15H10Cl2N2O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $45.00
  • MitoBloCK-10 | TIMM44 blocker

    MitoBloCK-10 (394694-98-5) is a first in class TIMM44 blocker. Translocase of inner mitochondrial membrane 44 (TIMM44) is essential for maintaining function and integrity of mitochondria.1 It […]

    From $60.00
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