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  • Focus Biomolecules cell signaling reagent supplier, chemical structure AM251 | Cannabinoid CB1 antagonist | CAS 183232-66-8
    $72.00
    AM251 (183232-66-8) is a potent cannabinoid CB1 receptor antagonist with selectivity over CB2 receptors (306-fold).1-3 Displays anorectic effects and antidepressant-like effects in mice.4 Behaves as an agonist at GPR55,...

  • Focus Biomolecules cell signaling supplier, chemical structure Synaptamide | Endogenous agonist at GPR110 | CAS 162758-94-3
    $30.00
    Synaptamide (162758-94-3) is an anandamide-like lipid mediator produced from DHA in the brain. Stimulates neurite growth, synaptogenesis and glutamatergic synaptic activity in developing hippocampal neurons at 10-100 nM.1...

  • Focus Biomolecules supplier, chemical structure of Diphenyleneiodonium chloride | Flavoprotein inhibitor | CAS 4673-26-1
    $0.00
    Diphenyleneiodonium chloride (4673-26-1) is an irreversible inhibitor of iNOS and eNOS (IC50s=50 and 100 nM respectively).1 Binds to and inhibits the flavoprotein of neutrophil NADPH oxidase.2 Novel agonist for GPR3.3...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of IPBT-5CA | GPR109B agonist | CAS 306935-41-1
    $35.00
    IPBT-5CA (306935-41-1) is a highly selective agonist for the human orphan G-protein-coupled receptor GPR109b (EC50 = 400 nM). No activity was reported at the highly homologous high-affinity niacin receptor GPR109a...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of MDL29,951 | GPR17 activator | CAS 130798-51-5
    $85.00
    MDL29,951 (130798-51-5) is a new, highly specific, small molecule activator of GPR171 that has been shown to be active in intact cells1. The ability to specifically activate GPR17 allows for the study of the exact role GPR17...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of NA-Gly | GPR18 agonist | CAS 179113-91-8
    $60.00
    NA-Gly (179113-91-8) is an endogenous anti-inflammatory lipo-amino acid1. Full agonist at GPR182,3. Induces macrophage apoptosis via GPR184 which may be a mechanism for its resolution of inflammation activity5...

  • Focus Biomolecules supplier, chemical structure of Oleoylethanolamide | GPR119 agonist: stimulates lipolysis | CAS 111-58-0
    $50.00
    Endogenous anandamide-like lipid acting as a PPARα agonist but does not bind to cannabinoid receptors.1 Biosynthesis via the action of NAPE-PLD on N-acylphosphatidylethanolamine.2 Agonist at GPR1193 and has been...

  • Pranlukast | Leukotriene CysLT1 antagonist / GPR17 antagonist
    $50.00
    Pranlukast (103177-37-3)is a selective Leukotriene CysLT1 antagonist1 and has been used in the treatment of asthma2. Pranlukast is also an inhibitor of GPR173 (IC50’s = 10.5nM hGPR17, 31nM rGPR17) and is superior to...

  • Focus Biomolecules cell signaling supplier, chemical structure Synaptamide | Endogenous agonist at GPR110 | CAS 162758-94-3
    $30.00
    Synaptamide (162758-94-3) is an anandamide-like lipid mediator produced from DHA in the brain. Stimulates neurite growth, synaptogenesis and glutamatergic synaptic activity in developing hippocampal neurons at 10-100 nM.1...

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