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  • AM251 | Cannabinoid CB1 antagonist
    AM251 (183232-66-8) is a potent cannabinoid CB1 receptor antagonist with selectivity over CB2 receptors (306-fold).1-3 Displays anorectic effects and antidepressant-like effects in mice.4 Behaves as an agonist at GPR55,...

  • Diphenyleneiodonium chloride | Flavoprotein inhibitor
    Diphenyleneiodonium chloride (4673-26-1) is an irreversible inhibitor of iNOS and eNOS (IC50s=50 and 100 nM respectively).1 Binds to and inhibits the flavoprotein of neutrophil NADPH oxidase.2 Novel agonist for GPR3.3...

  • IPBT-5CA | 306935-41-1 | Structure | Supplier
    IPBT-5CA (306935-41-1) is a highly selective agonist for the human orphan G-protein-coupled receptor GPR109b (EC50 = 400 nM). No activity was reported at the highly homologous high-affinity niacin receptor GPR109a...

  • MDL29,951 | GPR17 activator
    MDL29,951 (130798-51-5) is a new, highly specific, small molecule activator of GPR171 that has been shown to be active in intact cells1. The ability to specifically activate GPR17 allows for the study of the exact role GPR17...

  • NA-Gly | 179113-91-8 | Structure | Supplier
    NA-Gly (179113-91-8) is an endogenous anti-inflammatory lipo-amino acid1. Full agonist at GPR182,3. Induces macrophage apoptosis via GPR184 which may be a mechanism for its resolution of inflammation activity5...

  • Oleoylethanolamide | GPR119 agonist: stimulates lipolysis
    Endogenous anandamide-like lipid acting as a PPARα agonist but does not bind to cannabinoid receptors.1 Biosynthesis via the action of NAPE-PLD on N-acylphosphatidylethanolamine.2 Agonist at GPR1193 and has been...

  • Synaptamide | 162758-94-3 |Structure | Supplier
    Synaptamide (162758-94-3) is an anandamide-like lipid mediator produced from DHA in the brain. Stimulates neurite growth, synaptogenesis and glutamatergic synaptic activity in developing hippocampal neurons at 10-100 nM.1...

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