GTPase
Showing all 10 results
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Cellular trafficking
Dynasore | Dynamin inhibitor
Dynasore (304448-55-3) is a noncompetitive inhibitor of dynamin GTPase activity and blocks dynamin-dependent endocytosis in cells, including neuron...$40.00 – $160.00 Select options -
Cyclic Nucleotides
EPAC 5376753 | EPAC inhibitor
EPAC 5376753 is an allosteric inhibitor of Epac1, IC50= 4 μM.1 Does not inhibit PKA or adenylyl cyclase. Inhibits biological functions mediated by ...$60.00 – $240.00 Select options -
Cell Cycle
Mdivi | Mitochondrial division inhibitor
Mdivi (338967-87-6) is a selective inhibitor of Dnm1 GTPase (IC50=1-10 μM). Inhibits mitochondrial outer membrane permeabilization. Mdivi inhibits ...$40.00 – $160.00 Select options -
Autophagy
MiTMAB | Dynamin inhibitor
MiTMAB (1119-97-7) is a dynamin I/II inhibitor targeting the dynamin-phospholipid interaction and inhibiting dynamin GTPase activity with a Ki=940n...$55.00 – $180.00 Select options -
GTPase
MLS-532223 | GTPase inhibitor
MLS-532223 is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell pe...$62.00 – $248.00 Select options -
GTPase
MLS-573151 | Cdc42 inhibitor
MLS-573151 (10179-57-4) is a potent and specific inhibitor of Cdc42 a small GTPase of the Rho-subfamily (IC50=2 μM).1 A useful agent fpr probing th...$65.00 – $260.00 Select options -
Apoptosis
Nocodazole | Microtubule inhibitor
Nocodazole (31430-18-9) is an antimitotic agent that disrupts microtubules by binding to β tubulin and thereby inhibiting microtubule dynamics, dis...$50.00 – $170.00 Select options -
Cholinergics
NSC-23766 | Rac1 GTPase inhibitor
NSC-23766 (733767-34-5) is a selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange fact...$67.00 – $270.00 Select options -
Autophagy
Salirasib | Ras inhibitor
Salirasib (162520-00-5) is a synthetic farnesylcysteine mimetic that inhibits ras proteins1,2 via disruption of interactions between the S-Prenyl m...$30.00 – $120.00 Select options -
Cancer
Thiostrepton | Antibiotic and FOXM1 inhibitor
Thiostrepton (1393-48-2) is a novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase ...$85.00 – $340.00 Select options
