my account
Login
  Loading... Please wait...

Product Details

HPA | HDAC inhibitor

HPA (96017-59-3) is a histone deacetylase (HDAC) inhibitor, IC50=13 μM1. More potent and robust than valproic acid at inducing histone hyperacetylation (600% at 50 μM), HSP70 induction and protection against glutamate excitotoxicity in cultured neurons2. Cell permeable.

References/Citations
1) Eikel et al. (2006), Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives; Chem. Res. Toxicol., 19 272
2) Leng et al. (2010), Potent neuroprotective effects of novel structural derivatives of valproic acid: potential roles of HDAC inhibition and HSP70 induction; Neurosci. Lett., 476 127

swipe
Focus Biomolecules cell signaling reagent supplier, chemical structure of HPA | HDAC inhibitor | CAS 96017-59-3

Catalog#  10-1160-0020

$40.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
96017-59-3
Catalog Number:
10-1160
Activity:
HDAC inhibitor
Alternate Names:
HPA
Chemical Name:
2-(2-Propynyl)octanoic acid (racemic)
Molecular Weight:
182.27
Molecular Formula:
C11H18O2
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
Colorless oil
Purity:
97% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the HPA | HDAC inhibitor to your wish list.