Focus Biomolecules

  • GSK2656157 | PERK inhibitor

    CAS:
    1337532-29-2
    Catalog Number:
    10-4855
    Activity:
    PERK inhibitor
    Chemical Names:
    1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
    Molecular Weight:
    416.45
    Molecular Formula:
    C23H21FN6O
    Solubility:
    Soluble in DMSO (10 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
  • GSK2982772 | RIP1 inhibitor

    CAS:
    1622848-92-3
    Catalog Number:
    10-4792
    Activity:
    RIP1 kinase inhibitor
    Chemical Names:
    (S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2,4-traizole-3-carboxamide; GSK772
    Molecular Weight:
    377.40
    Molecular Formula:
    C20H19N5O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $95.00
  • IM-12 | GSK-3ß inhibitor

    CAS:
    1129669-05-1
    Catalog Number:
    10-5125
    Activity:
    GSK-3ß inhibitor
    Chemical Names:
    3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
    Molecular Weight:
    377.41
    Molecular Formula:
    C22H20FN3O2
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $52.00
  • Ipatasertib | pan-Akt inhibitor

    CAS:
    1001264-89-6
    Catalog Number:
    10-4751
    Activity:
    pan-Akt inhibitor
    Chemical Names:
    (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-yla,ino)propan-1-one; GDC-0068
    Molecular Weight:
    458.00
    Molecular Formula:
    C24H32ClN5O2
    Solubility:
    Soluble in DMSO (25 mg/mL) or ethanol (20 mg/mL)
    Physical Properties:
    Off-white to pale pink solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
  • Ki8751 | VEGFR2 inhibitor

    CAS:
    228559-41-9
    Catalog Number:
    10-4388
    Activity:
    VEGFR2 inhibitor
    Chemical Names:
    N-(2,4-Difluorophenyl)-N’-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea
    Molecular Weight:
    469.42
    Molecular Formula:
    C24H18F3N3O4
    Solubility:
    Soluble in DMSO (15 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $39.00
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