Decitabine | DNA hypomethylation agent

CAS:
2353-33-5
Catalog Number:
10-2412
Activity:
DNA hypomethylation agent
Alternate Names:
NSC-127716
Chemical Name:
5-Aza-2′-deoxycytidine
Molecular Weight:
228.21
Molecular Formula:
C8H12N4O4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Water (up to 11 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
10 mg$60.00
50 mg$200.00
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Decitabine (2353-33-5) inhibits DNA methyltransferase. Induces demethylation and reactivation of silenced genes. Increases stem cell reprogramming efficiency. Decitabine stimulates osteogenic differentiation of human bone marrow stromal cells. Antitumor agent. Cell permeable.

References/Citations:

1) Bender et al. (1998), Inhibition of DNA methylation by 5-aza-2′-deoxycytidine suppresses the growth of human tumor cell lines; Cancer Res., 58 95
2) El-Serafi et al. (2011), Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A; Differentiation, 81 35

CAS:
2353-33-5
Catalog Number:
10-2412
Activity:
DNA hypomethylation agent
Alternate Names:
NSC-127716
Chemical Name:
5-Aza-2′-deoxycytidine
Molecular Weight:
228.21
Molecular Formula:
C8H12N4O4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Water (up to 11 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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