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Product Details

FK-506 | FKBP inhibitor

FK-506 (104987-11-3) induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50 ~ 1 nM). Cell permeable.

References/Citations
1) Yu et al. (2006), Effects of cyclosporine A, FK506 and rapamycin on clacineurin phosphatase activity in mouse brain; IUBMB Life, 58 429

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Focus Biomolecules cell signaling reagent supplier, chemical structure of FK-506 | FKBP inhibitor | CAS 104987-11-3

Catalog#  10-1103

$100.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
104987-11-3
Catalog Number:
10-1103
Activity:
FKBP inhibitor
Alternate Names:
Tacrolimus
Molecular Weight:
804.04
Molecular Formula:
C44H69NO12
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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