PhysioProcesses

Natural products

‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).

  • Aphidicolin | DNA polymerase inhibitor

    CAS:
    38966-21-1
    Catalog Number:
    10-2058
    Activity:
    DNA polymerase inhibitor
    Chemical Name:
    (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol
    Molecular Weight:
    338.48
    Molecular Formula:
    C20H34O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 1 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $78.00
  • Apicidin | HDAC inhibitor

    CAS:
    183506-66-3
    Catalog Number:
    10-2057
    Activity:
    HDAC inhibitor
    Chemical Name:
    Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinexcarbonyl]
    Molecular Weight:
    623.78
    Molecular Formula:
    C34H49N5O6
    Solubility:
    Soluble in DMSO (up to 1 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. Compound is prone to oxidation. Protect from exposure to air.
    Shipping Code:
    RT
    From $55.00
  • Apigenin | Protein kinase inhibitor

    CAS:
    520-36-5
    Catalog Number:
    10-1242
    Activity:
    Protein kinase inhibitor
    Alternate Names:
    4,5,7-Trihydroxyflavone
    Chemical Name:
    5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
    Molecular Weight:
    270.24
    Molecular Formula:
    C15H10O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $36.00
  • Apoptolidin | Apoptosis inducer

    CAS:
    194874-06-1
    Catalog Number:
    10-2950
    Activity:
    Apoptosis inducer
    Source:
    Fermentation product from Amycolatopsis sp.
    Molecular Weight:
    1129.37
    Molecular Formula:
    C58H96O21
    Solubility:
    Soluble in DMSO, DMF, ethanol, or methanol.
    Physical Properties:
    White lyophilized solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, ethanol or methanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $248.00
  • Arecoline HBr | ACAT1 inhibitor

    CAS:
    300-08-3
    Catalog Number:
    10-1016
    Activity:
    ACAT1 inhibitor
    Chemical Names:
    1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic acid, methyl ester, hydrobromide
    Molecular Weight:
    236.11
    Molecular Formula:
    C8H13NO2·HBr
    Solubility:
    Soluble in Water (50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions are not stable – make fresh daily.
    Shipping Code:
    RT
    From $30.00
  • Ascomycin | FKBP ligand/Immunosuppressant

    CAS:
    11011-38-4
    Catalog Number:
    10-2059
    Activity:
    FKBP ligand; immunosuppressant
    Alternate Names:
    FK-520, FR-900520
    Chemical Name:
    Fermentation product from Streptomyces hygroscopicus
    Molecular Weight:
    729.03
    Molecular Formula:
    C43H69NO12
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $35.00
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