Cytokines

  • (5Z)-7-Oxozeaenol | TAK1 inhibitor

    CAS:
    253863-19-3
    Catalog Number:
    10-3023
    Activity:
    TAK1 inhibitor
    Chemical Names:
    (3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
    Alternate Name:
    LL-Z-1640-2
    Molecular Weight:
    362.38
    Molecular Formula:
    C19H22O7
    Solubility:
    Soluble in DMSO (9 mg/ml); ethanol (3 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $90.00
  • CDDO-Me | Nrf2 activator

    CAS:
    218600-53-4
    Catalog Number:
    10-5449
    Activity:
    Nrf2 activator
    Chemical Names:
    2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl ester
    Alternate Name:
    Bardoxolone methyl; NSC-713200; RTA 402; TP-155
    Molecular Weight:
    505.70
    Molecular Formula:
    C32H43NO4
    Solubility:
    Soluble in DMSO (25 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • CH-223191 | Arylhydrocarbon receptor antagonist

    CAS:
    301326-22-7
    Catalog Number:
    10-3089
    Activity:
    Arylhydrocarbon receptor antagonist
    Chemical Name:
    1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]-1H-pyrazole-5-carboxamide
    Molecular Weight:
    333.39
    Molecular Formula:
    C19H19N5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
    Physical Properties:
    Orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • DiMNF | AhR modulator (SAhRM)

    CAS:
    14756-24-2
    Catalog Number:
    10-1557
    Activity:
    AhR modulator (SAhRM)
    Chemical Name:
    2-(3,2-Dimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one
    Alternate Names:
    3’,4’-Dimethoxy-α-naphthoflavone
    Molecular Weight:
    332.45
    Molecular Formula:
    C21H16O4
    Solubility:
    Soluble in DMSO (up to 1.5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • GSK-J1 | JMJ H3K27 Demethylase inhibitor (Non-cell permeable)

    CAS:
    1373422-53-7
    Catalog Number:
    10-1393
    Activity:
    JMJ H3K27 Demethylase inhibitor (Non-cell permeable)
    Chemical Name:
    N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine
    Molecular Weight:
    389.46
    Molecular Formula:
    C22H23N5O2
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase  as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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