Cytokines

  • PF-4136309 | CCR2 antagonist

    CAS:
    1341224-83-6
    Catalog Number:
    10-4261
    Activity:
    CCR2 antagonist
    Chemical Name:
    N-[2-[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
    Alternate Name:
    INCB8761
    Molecular Weight:
    568.60
    Molecular Formula:
    C29H31F3N6O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • Reparixin | CXCR 1/2 allosteric antagonist

    CAS:
    266359-83-5
    Catalog Number:
    10-2527
    Activity:
    CXCR 1/2 allosteric antagonist
    Chemical Name:
    αR-Methyl-4-(2-methylpropyl)-N-(methylsulfonyl)-benzeneacetamide
    Alternate Names:
    DF 1681Y; Repertaxin
    Molecular Weight:
    283.39
    Molecular Formula:
    C14H21NO3S
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $52.00
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  • Ruboxistaurin

    CAS:
    169939-94-0
    Catalog Number:
    10-4354
    Molecular Weight:
    505.02
  • Ruxolitinib | JAK inhibitor

    CAS:
    941678-49-5
    Catalog Number:
    10-4511
    Activity:
    JAK inhibitor
    Alternate Names:
    INCB 018424
    Chemical Name:
    βR-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
    Molecular Weight:
    306.37
    Molecular Formula:
    C17H18N6
    Solubility:
    Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • SB 202190 | p38 MAP kinase inhibitor

    CAS:
    152121-30-7
    Catalog Number:
    10-2172
    Activity:
    p38 MAP kinase inhibitor
    Chemical Name:
    4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol
    Molecular Weight:
    331.35
    Molecular Formula:
    C20H14N3OF
    Solubility:
    Soluble in DMSO (up to 30 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $30.00
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