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Reversine | Reverses differentiated cells to multipotent stem cells

Reversine (656820-32-5) induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.1-2 Acts as a selective human A3 adenosine receptor antagonist (Ki = 0.66 μM).3 Cell permeable.

References/Citations
1) Chen et al. (2004), Dedifferentiation of lineage-committed cells by a small molecule; J. Am. Chem. Soc., 126 410
2) Chen et al. (2007), Reversine increases the plasticity of lineage-committed mammalian cells; Proc. Natl. Acad. Sci. USA, 104 10482
3) Perreira et al. (2005), Reversine and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists; J. Med. Chem., 48 4910

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Reversine | 656820-32-5 | Structure | Supplier

Catalog#  10-1154

$27.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
656820-32-5
Catalog Number:
10-1154
Activity:
Reverses differentiated cells to multipotent stem cells
Chemical Name:
2-(4-Morpholinoanilino)-6-cyclohexylaminopurine
Molecular Weight:
383.5
Molecular Formula:
C21H27N7O
Solubility:
Soluble in DMSO (up to 7 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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