1-Aminobenzotriazole | Cytochrome P450 inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 50 mg | $50.00 | ||
| 250 mg | $185.00 |
1-Aminobenztriazole (1614-12-6) is a pan-specific cytochrome P450 inhibitor acting as a suicide substrate.1,2 Blocks omega-oxidation of arachidonic acid but not its epoxidation.3
References/Citations:
1) Mugford et al. (1995), 1-Aminobenzotriazole-Induced Destruction of Hepatic and Renal Cytochrome P450 in Male Sprague-Dawley Rats; Fundam. Appl. Tox., 19 43
2) Emoto et al. (2005), In Vitro Inhibitory Effect of 1-Aminobenzotriazole on Drug Oxidations in Human Liver Microsomes: A Comparison With SKF-525A; Drug Metab. Pharmacokinet., 20 351
3) Su et al. (1998), Inhibition of Renal Arachidonic Acid Omega-Hydroxylase Activity With ABT Reduces Blood Pressure in the SHR; Am. J. Physiol., 275 R426
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
1-Aminobenztriazole (1614-12-6) is a pan-specific cytochrome P450 inhibitor acting as a suicide substrate.1,2 Blocks omega-oxidation of arachidonic acid but not its epoxidation.3
References/Citations:
1) Mugford et al. (1995), 1-Aminobenzotriazole-Induced Destruction of Hepatic and Renal Cytochrome P450 in Male Sprague-Dawley Rats; Fundam. Appl. Tox., 19 43
2) Emoto et al. (2005), In Vitro Inhibitory Effect of 1-Aminobenzotriazole on Drug Oxidations in Human Liver Microsomes: A Comparison With SKF-525A; Drug Metab. Pharmacokinet., 20 351
3) Su et al. (1998), Inhibition of Renal Arachidonic Acid Omega-Hydroxylase Activity With ABT Reduces Blood Pressure in the SHR; Am. J. Physiol., 275 R426
Related products
-
PF-622 | FAAH inhibitor
From $60.00CAS:898235-65-9Catalog Number:10-1299Activity:FAAH inhibitorChemical Name:N-Phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamideMolecular Weight:346.44Molecular Formula:C21H22N4OSolubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 3 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
Phytosphingosine | Natural sphingolipid
From $45.00CAS:554-62-1Catalog Number:10-1227Activity:Natural sphingolipidAlternate Names:4-HydroxysphinganineChemical Name:(2S,3R,4R)-Octadecane-1,2,3,4-tetraolMolecular Weight:317.52Molecular Formula:C18H39NO3Solubility:Soluble in Ethanol (up to 2 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
MK-571 | Cys LT1 antagonist
From $60.00CAS:115104-28-4Catalog Number:10-1039Activity:Cys LT1 antagonistAlternate Names:L-660711Chemical Name:5-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acidMolecular Weight:515.09Molecular Formula:C26H27ClN2O3S2Solubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:Yellow solidPurity:95% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
