1-Aminobenzotriazole | Cytochrome P450 inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 50 mg | $50.00 | ||
| 250 mg | $185.00 |
1-Aminobenztriazole (1614-12-6) is a pan-specific cytochrome P450 inhibitor acting as a suicide substrate.1,2 Blocks omega-oxidation of arachidonic acid but not its epoxidation.3
References/Citations:
1) Mugford et al. (1995), 1-Aminobenzotriazole-Induced Destruction of Hepatic and Renal Cytochrome P450 in Male Sprague-Dawley Rats; Fundam. Appl. Tox., 19 43
2) Emoto et al. (2005), In Vitro Inhibitory Effect of 1-Aminobenzotriazole on Drug Oxidations in Human Liver Microsomes: A Comparison With SKF-525A; Drug Metab. Pharmacokinet., 20 351
3) Su et al. (1998), Inhibition of Renal Arachidonic Acid Omega-Hydroxylase Activity With ABT Reduces Blood Pressure in the SHR; Am. J. Physiol., 275 R426
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
1-Aminobenztriazole (1614-12-6) is a pan-specific cytochrome P450 inhibitor acting as a suicide substrate.1,2 Blocks omega-oxidation of arachidonic acid but not its epoxidation.3
References/Citations:
1) Mugford et al. (1995), 1-Aminobenzotriazole-Induced Destruction of Hepatic and Renal Cytochrome P450 in Male Sprague-Dawley Rats; Fundam. Appl. Tox., 19 43
2) Emoto et al. (2005), In Vitro Inhibitory Effect of 1-Aminobenzotriazole on Drug Oxidations in Human Liver Microsomes: A Comparison With SKF-525A; Drug Metab. Pharmacokinet., 20 351
3) Su et al. (1998), Inhibition of Renal Arachidonic Acid Omega-Hydroxylase Activity With ABT Reduces Blood Pressure in the SHR; Am. J. Physiol., 275 R426
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