2-Bromopalmitic acid | Palmitoylation inhibitor

CAS:
18263-25-7
Catalog Number:
10-3284
Activity:
Palmitoylation inhibitor
Chemical Name:
2-Bromohexadecanoic acid (racemic)
Alternate Names:
2-BP
Molecular Weight:
335.23
Molecular Formula:
C16H31BrO2
Solubility:
Soluble in DMSO (up to 75 mg/ml) or in Ethanol (up to 25 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
500 mg$45.00
2 gram$120.00

2-Bromopalmitic acid (18263-25-7) inhibits protein S-palmitoylation.1 Blocks palmitic acid-induced increase in cAMP levels in human primary melanocytes expressing the melanocortin-1 receptor which undergoes an essential palmitoylation as a prerequisite for receptor signaling.2

References/Citations:

1) Tsukamoto et al. (2013), Role of S-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells; PLoS One, 8(9) e75831
2) Chen et al. (2017), Palmitoylation-dependent activation of MC1R prevents melanomagenesis; Nature, 549 399

CAS:
18263-25-7
Catalog Number:
10-3284
Activity:
Palmitoylation inhibitor
Chemical Name:
2-Bromohexadecanoic acid (racemic)
Alternate Names:
2-BP
Molecular Weight:
335.23
Molecular Formula:
C16H31BrO2
Solubility:
Soluble in DMSO (up to 75 mg/ml) or in Ethanol (up to 25 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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