24(S),25-Epoxycholesterol | LXR agonist
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $105.00 | ||
| 5 mg | $430.00 |
24(S),25-Epoxycholesterol (77058-74-3) is a cholesterol metabolite that acts as an endogenous agonist for nuclear receptor LXR.1 Controls cellular cholesterol homeostasis.2 24(S),25-Epoxycholesterol promotes neural development in zebra fish as well as dopaminergic differentiation of embryonic stem cells.3 Cell permeable.
References/Citation:
1) Chawla et al. (2001), Nuclear receptors and lipid physiology: opening the X-files; Science, 294 1866
2) Brown et al. (2009), 24(S),25-epoxycholesterol: a messenger for cholesterol homeostasis; Int. J. Biochem. Cell Biol., 41 744
3) Theofilopoulos et al. (2013), Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis; Nature Chem. Biol., 9 126
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
24(S),25-Epoxycholesterol (77058-74-3) is a cholesterol metabolite that acts as an endogenous agonist for nuclear receptor LXR.1 Controls cellular cholesterol homeostasis.2 24(S),25-Epoxycholesterol promotes neural development in zebra fish as well as dopaminergic differentiation of embryonic stem cells.3 Cell permeable.
References/Citation:
1) Chawla et al. (2001), Nuclear receptors and lipid physiology: opening the X-files; Science, 294 1866
2) Brown et al. (2009), 24(S),25-epoxycholesterol: a messenger for cholesterol homeostasis; Int. J. Biochem. Cell Biol., 41 744
3) Theofilopoulos et al. (2013), Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis; Nature Chem. Biol., 9 126
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1-855-FOCUS21
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