Size | Price | Quantity | |
---|---|---|---|
10mg | $85.00 | ||
50mg | $325.00 |
Vaccine adjuvants are materials that enhance the magnitude and duration of protective immune responses, typically via pattern recognition receptors (PRR). 2E151 (2416963-37-4) is a co-adjuvant that increases the potency of toll-like receptor (TLR) adjuvants and overall enhances T cell stimulation/proliferation and cytokine production.1 Its increases intracellular Ca2+ via extracellular Ca2+ influx, leading to NF-kB activation (EC50 = 0.9 µM)2 via IKK/MAPK phosphorylation and NFAT translocation in B cells and monocytes.
References/Citations:
C26H31N3O3S2
98% HPLC
NMR (Conforms)
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Vaccine adjuvants are materials that enhance the magnitude and duration of protective immune responses, typically via pattern recognition receptors (PRR). 2E151 (2416963-37-4) is a co-adjuvant that increases the potency of toll-like receptor (TLR) adjuvants and overall enhances T cell stimulation/proliferation and cytokine production.1 Its increases intracellular Ca2+ via extracellular Ca2+ influx, leading to NF-kB activation (EC50 = 0.9 µM)2 via IKK/MAPK phosphorylation and NFAT translocation in B cells and monocytes.
References/Citations:
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Concentration × Volume × Molecular Weight = Mass
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