3-Aminobenzamide | PARP inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 1 gram | $50.00 |
3-Aminobenzamide (3544-24-9) inhibits endogenous poly-ADP-ribosyltransferases.1 Inhibits nitric oxide-induced apoptosis but not differentiation in HL-60 cells.2 Inhibits stress-induced apoptosis.3 3-Aminobenzamide has been shown to protect cells from oxygen radical and nitric oxide toxicity.4
References/Citations:
1) Purnell and Whish (1980), Novel inhibitors of poly(ADP-ribose) synthetase; Biochem. J., 185 775
2) Kuo et al. (1996), Inhibitors of poly(ADP-ribose) polymerase block nitric oxide-induced apoptosis but not differentiation in human leukemia HL-60 cells; Biochem. Biophys. Res. Commun., 219 502
3) Malorni et al. (1995), 3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion; Biochem. Biophys. Res. Commun., 207 715
4) Heller et al. (1995), Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells; J. Biol. Chem., 270 11176
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
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3-Aminobenzamide (3544-24-9) inhibits endogenous poly-ADP-ribosyltransferases.1 Inhibits nitric oxide-induced apoptosis but not differentiation in HL-60 cells.2 Inhibits stress-induced apoptosis.3 3-Aminobenzamide has been shown to protect cells from oxygen radical and nitric oxide toxicity.4
References/Citations:
1) Purnell and Whish (1980), Novel inhibitors of poly(ADP-ribose) synthetase; Biochem. J., 185 775
2) Kuo et al. (1996), Inhibitors of poly(ADP-ribose) polymerase block nitric oxide-induced apoptosis but not differentiation in human leukemia HL-60 cells; Biochem. Biophys. Res. Commun., 219 502
3) Malorni et al. (1995), 3-Aminobenzamide protects cells from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion; Biochem. Biophys. Res. Commun., 207 715
4) Heller et al. (1995), Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells; J. Biol. Chem., 270 11176
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