3-Cyano-7-ethoxycoumarin | CYP450 fluorescent substrate

CAS:
11620-77-6
Catalog Number:
10-1440
Activity:
CYP450 fluorescent substrate
Chemical Name:
7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile
Molecular Weight:
215.20
Molecular Formula:
C12H9O3
Solubility:
Soluble in DMSO (up to 20 mg/ml with warming) or in Ethanol (up to 3 mg/ml with warming)
Physical Properties:
Pale Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
10 mg$75.00
50 mg$300.00

3-Cyano-7-ethoxycoumarin (11620-77-6) is a fluorescent substrate for cytochrome P450. Excitation/emission =  408/455 nm.1 May be used for CYP1A2 and CYP2C19 in intact cells.2 Cell permeable

References/Citations:

1) White et al. (1988), A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin;  Anal. Biochem., 172 304
2) Donato et al. (2004), Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes;  Drug Metab. Dispos., 32 699

CAS:
11620-77-6
Catalog Number:
10-1440
Activity:
CYP450 fluorescent substrate
Chemical Name:
7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile
Molecular Weight:
215.20
Molecular Formula:
C12H9O3
Solubility:
Soluble in DMSO (up to 20 mg/ml with warming) or in Ethanol (up to 3 mg/ml with warming)
Physical Properties:
Pale Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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