6-Formylindolo[3,2-b]carbazole (FICZ) | AhR endogenous agonist

CAS:
172922-91-7
Catalog Number:
10-1463
Activity:
AhR endogenous agonist
Alternate Names:
FICZ
Molecular Weight:
284.32
Molecular Formula:
C19H12N2O
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Yellow solid
Purity:
95% by TLC
NMR (Conforms)
Storage Temperature:
-80°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
500 µg$54.00
1 mg$98.00

6-Formylindolo(3,2-b)carbazole (FICZ) (172922-91-7) is a very potent (Kd = 0.07 nM) endogenous ligand for the aryl hydrocarbon receptor (AhR).1,2

References/Citations:

1) Rannung et al. (1987) Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances; J. Biol. Chem., 262 15422
.2) Wincent et al. (2009) The Suggested Physiologic Aryl Hydrocarbon Receptor Activator and Cytochrome P4501 Substrate 6-Formylindolo[3,2-b}carbazole is Present in Humans; J. Biol. Chem., 284 2690

CAS:
172922-91-7
Catalog Number:
10-1463
Activity:
AhR endogenous agonist
Alternate Names:
FICZ
Molecular Weight:
284.32
Molecular Formula:
C19H12N2O
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Yellow solid
Purity:
95% by TLC
NMR (Conforms)
Storage Temperature:
-80°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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