8-Oxo-2′-deoxyguanosine | Marker for DNA damage
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $38.00 | ||
| 5 mg | $160.00 |
8-Oxo-2′-deoxyguanosine (88847-89-6) is a useful marker for DNA damage via a variety of oxidative processes.1 It is a critical biomarker for oxidative stress and carcinogenesis.2,3
References/Citations:
1) Beckman et al. (1997), Oxidative decay of DNA; J. Biol. Chem., 272 19636
2) Andreoli et al. (2010), Quantitative determination of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile for healthy volunteers; Biomarkers, 15 221
3) Manini et al. (2009), Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers; Toxicol. Lett., 190 41
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
8-Oxo-2′-deoxyguanosine (88847-89-6) is a useful marker for DNA damage via a variety of oxidative processes.1 It is a critical biomarker for oxidative stress and carcinogenesis.2,3
References/Citations:
1) Beckman et al. (1997), Oxidative decay of DNA; J. Biol. Chem., 272 19636
2) Andreoli et al. (2010), Quantitative determination of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile for healthy volunteers; Biomarkers, 15 221
3) Manini et al. (2009), Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers; Toxicol. Lett., 190 41
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