9-Hydroxyrisperidone | Risperidone metabolite

CAS:
144598-75-4
Catalog Number:
10-2300
Activity:
Risperidone metabolite
Chemical Name:
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Alternate Name:
Paliperidone
Molecular Weight:
426.48
Molecular Formula:
C23H27FN4O3
Solubility:
Soluble in DMSO (up to 4 mg/ml).
Physical Properties:
White solid
Purity:
95% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
10 mg$30.00
50 mg$110.00

9-Hydroxyrisperidone (144598-75-4) is a pharmacologically active metabolite of risperidone, an atypical antipsychotic agent.1 Displays high affinity for serotonin 5-HT2A receptors as well as dopamine D2 receptors.2,3

References/Citations:

1) Beijsterveldt et al. (1994), Regional brain distribution of risperidone and its active metabolite 9-hydroxy-risperidone in the rat; Psychopharmacology, 114 53
2) Leysen et al. (1994), Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity; J. Clin. Psychiatry, 55 suppl: 5
3) Schotte et al. (1996), Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding; Psychopharmacology (Berl.), 124 57

CAS:
144598-75-4
Catalog Number:
10-2300
Activity:
Risperidone metabolite
Chemical Name:
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Alternate Name:
Paliperidone
Molecular Weight:
426.48
Molecular Formula:
C23H27FN4O3
Solubility:
Soluble in DMSO (up to 4 mg/ml).
Physical Properties:
White solid
Purity:
95% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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