Aflatoxin B1 | Mycotoxin

CAS:
 1162-65-8
Catalog Number:
 10-3504
Alfatoxin B1 chemical structure

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Aflatoxin B1 (1162-65-8) is a highly toxic, carcinogenic mycotoxin produced by Aspergillus parasiticus and Aspergillus flavus.1 In the liver Aflatoxin B1 is converted to an epoxide (aflatoxin B1-8,9-epoxide) which is highly reactive and forms conjugates with DNA, RNA, thiols, and proteins.2  Aflatoxin B1 reactive metabolites drive oxidative stress, inflammation and apoptosis.3  Warning: TOXIC. Avoid exposure by all routes.

References/Citations:

  1. Rushing and Selim (2019), Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods; Food Chem. Toxicol. 124 81
  2. McLean and Dutton (1995), Cellular interactions and metabolism of aflatoxin: An update; Pharmacol. Ther. 65 163
  3. Kabali et al. (2026), Alleviation of Aflatoxin B1-Induced Hepatic Damage by Propolis: Effects on Inflammation, Apoptosis, and Cytochrome P450 Enzyme Expression; Curr. Issues Mol. Biol. 48 56
1162-65-8, Aflatoxin, Aflatoxin B1, Aflatoxin B1 supplier
CAS:
1162-65-8
Catalog Number:
10-3504
Activity:
Mycotoxin
Chemical Names:
(6aR,9aS)-4-Methoxy-2,3-dihydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11(6aH,9aH)-dione
Molecular Weight:
312.28
Molecular Formula:

C17H12O6

Solubility:
Soluble in DMSO (30 mg/ml); Chloroform (40 mg/ml)
Physical Properties:
White solid
Purity:

>98% HPLC
NMR: (Conforms)

Storage Temperature:
-20°C
Stability:
Stable for up to 2 years when stored as supplied @ -20°C. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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Aflatoxin B1 (1162-65-8) is a highly toxic, carcinogenic mycotoxin produced by Aspergillus parasiticus and Aspergillus flavus.1 In the liver Aflatoxin B1 is converted to an epoxide (aflatoxin B1-8,9-epoxide) which is highly reactive and forms conjugates with DNA, RNA, thiols, and proteins.2  Aflatoxin B1 reactive metabolites drive oxidative stress, inflammation and apoptosis.3  Warning: TOXIC. Avoid exposure by all routes.

References/Citations:

  1. Rushing and Selim (2019), Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods; Food Chem. Toxicol. 124 81
  2. McLean and Dutton (1995), Cellular interactions and metabolism of aflatoxin: An update; Pharmacol. Ther. 65 163
  3. Kabali et al. (2026), Alleviation of Aflatoxin B1-Induced Hepatic Damage by Propolis: Effects on Inflammation, Apoptosis, and Cytochrome P450 Enzyme Expression; Curr. Issues Mol. Biol. 48 56

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