AG-879 | NGFR kinase inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 5mg | $70.00 | ||
| 25mg | $280.00 |
AG-879 (148741-30-4) inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 μM). No inhibition of EGF, or PDGF receptor phosphorylation is observed at typical working concentrations.
References/Citations:
1) Ohmichi et al. (1993), The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor; Biochemistry, 32 4650
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
AG-879 (148741-30-4) inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 μM). No inhibition of EGF, or PDGF receptor phosphorylation is observed at typical working concentrations.
References/Citations:
1) Ohmichi et al. (1993), The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor; Biochemistry, 32 4650
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