AG-879 | NGFR kinase inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 5mg | $70.00 | ||
| 25mg | $280.00 |
AG-879 (148741-30-4) inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 μM). No inhibition of EGF, or PDGF receptor phosphorylation is observed at typical working concentrations.
References/Citations:
1) Ohmichi et al. (1993), The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor; Biochemistry, 32 4650
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
AG-879 (148741-30-4) inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 μM). No inhibition of EGF, or PDGF receptor phosphorylation is observed at typical working concentrations.
References/Citations:
1) Ohmichi et al. (1993), The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor; Biochemistry, 32 4650
Related products
-
DMPQ 2HCl | PDGFR inhibitor
From $65.00CAS:1123491-15-5Catalog Number:10-1370Activity:PDGFR inhibitorChemical Name:5,7-Dimethoxy-3-(4-pyridinyl)quinolone dihydrochlorideMolecular Weight:339.22Molecular Formula:C16H14N2O2 2HClSolubility:Soluble in DMSO (up to 1 mg/ml with warming) or in Water (up to 30 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.Shipping Code:RT -
SU-5402 | FGFR Phosphorylation inhibitor
From $70.00CAS:215543-92-3Catalog Number:10-2520Activity:FGFR Phosphorylation inhibitorAlternate Names:PF-02969207Chemical Name:3-[4-Methyl-2-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acidMolecular Weight:296.32Molecular Formula:C17H16N2O3Solubility:Soluble in DMSO (up to 10 mg/ml).Physical Properties:Orange solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
LM22A-4 | TrkB small molecule agonist
From $50.00CAS:37988-18-4Catalog Number:10-1405Activity:TrkB small molecule agonistChemical Name:N,N’,N’ Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamideMolecular Weight:339.35Molecular Formula:C15H21N3O6Solubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
