Alamethicin | Pore-forming antimicrobial peptide
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $44.00 | ||
| 5 mg | $114.00 |
Alamethicin (27061-78-5) is a membrane permeabilizing, pore-forming agent.1 Applications include: [32P] incorporation into phosphatidylinositols2, permeabilization of sarcoplasmic reticulum vesicles3 and mitochondria4 and induction of lipid vesicle fusion.
References/Citations:
1) Woolley et al. (2007), Channel-forming activity of alamethicin: effects of covalent tethering; Biodivers., 4 1323
2) Quist et al. (1989), Regulation of polyphosphoinositide synthesis in cardiac membranes; Arch. Biochem. Biophys., 271 21
3) Nakagawa et al. (1986), Adenylate cyclase in sarcoplasmic reticulum of skeletal muscle: distribution orientation and regulation; J. Cyclic Nuc. Prot. Phosphor. Res., 11 237
4) Korge et al. (2016), Reactive oxygen species production in cardiac mitochondria after complex I inhibition: Modulation by substrate-dependent regulation of the NADH/NAD(+) ratio; Free Radic. Biol. Med., 96 22
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Alamethicin (27061-78-5) is a membrane permeabilizing, pore-forming agent.1 Applications include: [32P] incorporation into phosphatidylinositols2, permeabilization of sarcoplasmic reticulum vesicles3 and mitochondria4 and induction of lipid vesicle fusion.
References/Citations:
1) Woolley et al. (2007), Channel-forming activity of alamethicin: effects of covalent tethering; Biodivers., 4 1323
2) Quist et al. (1989), Regulation of polyphosphoinositide synthesis in cardiac membranes; Arch. Biochem. Biophys., 271 21
3) Nakagawa et al. (1986), Adenylate cyclase in sarcoplasmic reticulum of skeletal muscle: distribution orientation and regulation; J. Cyclic Nuc. Prot. Phosphor. Res., 11 237
4) Korge et al. (2016), Reactive oxygen species production in cardiac mitochondria after complex I inhibition: Modulation by substrate-dependent regulation of the NADH/NAD(+) ratio; Free Radic. Biol. Med., 96 22
Related products
-
PK150 | Sorafenib analog with unique antibacterial properties
From $55.00CAS:2165324-62-7Catalog Number:10-3960Activity:Sorafenib analog with unique antibacterial propertiesChemical Name:1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)ureaMolecular Weight:394.68Molecular Formula:C15H8ClF5N2O3Solubility:Soluble in DMSO (up to at least 25 mg/ml).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
Tigecycline | Antibiotic
From $50.00CAS:220620-09-7Catalog Number:10-3900Activity:AntibioticChemical Name:(4S,4aS,5aR,12aR)-9-[[2-(tert-Butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamideAlternate Names:9-t-Butylglycylamidominocycline; GAR-936Molecular Weight:585.66Molecular Formula:C29H39N5O8Solubility:Soluble in DMSO (up to at least 25 mg/ml).Physical Properties:Orange solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
IMP-1700 | Bacterial DNA repair inhibitor
From $60.00CAS:1458674-25-3Catalog Number:10-3950Activity:Bacterial DNA repair inhibitorChemical Name:1-Cyclopropyl-6-fluoro-4-oxo-7-(4-(4-(trifluoromethyl)phenyl)carbamothioyl)piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acidMolecular Weight:534.53Molecular Formula:C25H22F4N4O5SSolubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
