Aripiprazole | Dopamine receptor partial agonist

CAS:
129722-12-9
Catalog Number:
10-2314
Activity:
Dopamine receptor partial agonist
Alternate Names:
OPC-14597
Chemical Name:
7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
Molecular Weight:
448.4
Molecular Formula:
C23H27Cl2N3O2
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
20 mg$40.00
100 mg$100.00

Aripiprazole (129722-12-9) is a clinically useful neuroleptic and antipsychotic agent.1 Dopamine D2 receptor antagonist and autoreceptor agonist.Improves symptoms of psychosis associated with Alzheimer’s disease.3 Aripiprazole blocked cocaine-seeking behavior without affecting other rewarding behaviors in animal models.4

References/Citations:

1) Green et al. (2004), Focus on aripiprazole; Curr. Med. Res. Opin., 20 207
2)
Kikuchi et al. (1995), 7-(4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro-2(1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity; J. Pharmacol. Exp. Ther., 274 329
3)
Madhusoodanan et al. (2008), Management of psychosis in patients with Alzheimer’s disease: focus on aripiprazole; Clin. Interv. Aging, 3 491
4)
Feltenstein et al. (2007), Aripiprazole blocks reinstatement of cocaine seeking in an animal model of relapse; Biol. Psychiatry, 61 582

CAS:
129722-12-9
Catalog Number:
10-2314
Activity:
Dopamine receptor partial agonist
Alternate Names:
OPC-14597
Chemical Name:
7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
Molecular Weight:
448.4
Molecular Formula:
C23H27Cl2N3O2
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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