AS-041164 | PI3Kgamma inhibitor

CAS:
6318-41-8
Catalog Number:
10-1035
Activity:
PI3Kγ inhibitor
Chemical Name:
5-(1,3-Benzodioxol-5-yl)methylidene-1,3-thiazolidine-2,4-dione
Molecular Weight:
249.24
Molecular Formula:
C11H7NO4S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$54.00
25 mg$160.00

AS-041164 (6318-41-8) is a potent, ATP-competitive, and isoform-selective PI3-Kinase inhibitor (IC50 = 0.07, 0.24, 1.45, and 1.70 μM for the γ, α, β, and δ isoforms respectively).1 Cell permeable.

References/Citations:

1) Ferrandi et al. (2007) Phosphoinositide 3-kinase gamma inhibition plays a crucial role in early steps of inflammation by blocking neutrophil recruitment: J. Pharmacol. Exp. Ther. 322 923

CAS:
6318-41-8
Catalog Number:
10-1035
Activity:
PI3Kγ inhibitor
Chemical Name:
5-(1,3-Benzodioxol-5-yl)methylidene-1,3-thiazolidine-2,4-dione
Molecular Weight:
249.24
Molecular Formula:
C11H7NO4S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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