BAY-1797 | P2X4 antagonist

CAS:
2055602-83-8
Catalog Number:
10-3980
Activity:
P2X4 antagonist
Chemical Names:
N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide
Molecular Weight:
416.88
Molecular Formula:
C20H17ClN2O4S
Solubility:
Soluble in DMSO (>25 mg/ml)
Physical Properties:
Pale brown solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$75.00
25 mg$325.00
This product is also available in the following library:

BAY-1797 (2055602-83-8) is a selective P2X4 receptor antagonist (IC50 = 211 nM HEK cellular assay; P2X4 calcium influx based assays – hIC50 = 108 nM, mIC50 = 112 nM, rIC50 = 233 nM).1 Displayed antinociceptive and anti-inflammatory effects in mouse CFA inflammatory pain models. 

References/Citations:

  1. Werner et al. (2019) Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile; J. Med. Chem. 62 11194
CAS:
2055602-83-8
Catalog Number:
10-3980
Activity:
P2X4 antagonist
Chemical Names:
N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide
Molecular Weight:
416.88
Molecular Formula:
C20H17ClN2O4S
Solubility:
Soluble in DMSO (>25 mg/ml)
Physical Properties:
Pale brown solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

20% OFF

For Postdoc
Customers!