Benzamidine HCl | Trypsin and serine protease inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 g | $30.00 | ||
| 25 g | $75.00 |
Benzamidine HCl (1670-14-0) is a reversible inhibitor of trypsin and trypsin-like enzymes and other serine proteases.1-3 Concentration used for general protease inhibition is 1 mM. Also a competitive inhibitor of thrombin and plasmin. May be added to blood samples to prevent proteolytic degradation of various peptide analytes such as glucagon4 and TRH5.
References/Citations:
1) Markwardt et al. (1968) Comparative studies on the inhibition of trypsin, plasmin, and thrombin by derivatives of benzylamine and benzamide; Eur. J. Biochem., 6 502
2) Deutscher et al. (1990), Maintaining protein stability; Methods Enzymol., 182 83
3) Jaswinski et al. (1990), Preparations of extracts from yeast; Methods Enzymol., 182 154
4) Ensinck et al. (1972), Use of Benzamidine as a proteolytic inhibitor in the radioimmunoassay of glucagon in plasma; J. Clin. Endocrinol. Metab., 35 463
5) Jeffcoate et al. (1974), Use of benzamidine to prevent the destruction of thyrotropin-releasing hormone (TRH) by blood; Endocrinol. Metab, 38 155
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Benzamidine HCl (1670-14-0) is a reversible inhibitor of trypsin and trypsin-like enzymes and other serine proteases.1-3 Concentration used for general protease inhibition is 1 mM. Also a competitive inhibitor of thrombin and plasmin. May be added to blood samples to prevent proteolytic degradation of various peptide analytes such as glucagon4 and TRH5.
References/Citations:
1) Markwardt et al. (1968) Comparative studies on the inhibition of trypsin, plasmin, and thrombin by derivatives of benzylamine and benzamide; Eur. J. Biochem., 6 502
2) Deutscher et al. (1990), Maintaining protein stability; Methods Enzymol., 182 83
3) Jaswinski et al. (1990), Preparations of extracts from yeast; Methods Enzymol., 182 154
4) Ensinck et al. (1972), Use of Benzamidine as a proteolytic inhibitor in the radioimmunoassay of glucagon in plasma; J. Clin. Endocrinol. Metab., 35 463
5) Jeffcoate et al. (1974), Use of benzamidine to prevent the destruction of thyrotropin-releasing hormone (TRH) by blood; Endocrinol. Metab, 38 155
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