Blasticidin S HCl | Antibiotic selection agent
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 20 mg | $80.00 | ||
| 100 mg | $200.00 |
Blasticidin S HCl (3513-03-9) is a peptidyl nucleoside antibiotic inhibiting protein synthesis in bacteria and eukaryotes.1 Inhibits translation by trapping deformed tRNA on the ribosome.1 The ABC-type transporter NppA1A2BCD is required for uptake of blasticidin S and other peptidyl nucleoside antibiotics in Pseudomonas aeruginosa PA14.2 Selection agent for bis, bsr and bsd transformed cells.3,4
References/Citations:
1) Svidritskiy et al., (2013), Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome; Proc. Natl. Acad. Sci. USA 110 12283
2) Pletzer et al. (2015), The Pseudomonas aeruginosa PA14 ABC Transporter NppA1A2BCD is Required for Uptake of Peptidyl Nucleoside Antibiotics; J. Bacteriol. 197 2217
3) Asada et al. (2015), Transfection of Babesia bovis by Double Selection with WR99210 and Blasticidin-S and Its Application for Functional Analysis of Thioredoxin Peroxidase-1; PLoS One, 10 e0125993
4) Garg and Qadri (2010), Hemoglobin transforms anti-inflammatory Salmonella typhi virulence polysaccharide into a TLR-2 agonist; J. Immunol. 184 5980
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Blasticidin S HCl (3513-03-9) is a peptidyl nucleoside antibiotic inhibiting protein synthesis in bacteria and eukaryotes.1 Inhibits translation by trapping deformed tRNA on the ribosome.1 The ABC-type transporter NppA1A2BCD is required for uptake of blasticidin S and other peptidyl nucleoside antibiotics in Pseudomonas aeruginosa PA14.2 Selection agent for bis, bsr and bsd transformed cells.3,4
References/Citations:
1) Svidritskiy et al., (2013), Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome; Proc. Natl. Acad. Sci. USA 110 12283
2) Pletzer et al. (2015), The Pseudomonas aeruginosa PA14 ABC Transporter NppA1A2BCD is Required for Uptake of Peptidyl Nucleoside Antibiotics; J. Bacteriol. 197 2217
3) Asada et al. (2015), Transfection of Babesia bovis by Double Selection with WR99210 and Blasticidin-S and Its Application for Functional Analysis of Thioredoxin Peroxidase-1; PLoS One, 10 e0125993
4) Garg and Qadri (2010), Hemoglobin transforms anti-inflammatory Salmonella typhi virulence polysaccharide into a TLR-2 agonist; J. Immunol. 184 5980
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