BML-260 | JSP-1 phosphatase inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $55.00 | ||
| 25 mg | $200.00 |
BML-260 (101439-76-3) is a potent inhibitor of the dual specificity phosphatase JSP-1 (IC50= 18 µM).1 It promotes the growth of cord blood and mobilizes peripheral blood hematopoietic stem and progenitor cells.2 It increases UCP1 expression in both brown and white adipocytes increasing mitochondrial activity and heat generation, an effect that is JSP-1 independent.3
References/Citations:
- Cutshall et al. (2005), Rhodanine derivatives as inhibitors of JSP-1; Bioorg. Med. Chem. Lett., 15 3374
- Albayrak et al. (2022), BML-260 promotes the growth of cord blood and mobilized peripheral blood hematopoietic stem and progenitor cells with improved reconstitution ability; J. Cell. Biochem., 123 2009
- Feng et al. (2019), Identification of a rhodamine derivative BML-260 as a potent stimulator of UCP1 expression; Theranostics, 9 3501
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
BML-260 (101439-76-3) is a potent inhibitor of the dual specificity phosphatase JSP-1 (IC50= 18 µM).1 It promotes the growth of cord blood and mobilizes peripheral blood hematopoietic stem and progenitor cells.2 It increases UCP1 expression in both brown and white adipocytes increasing mitochondrial activity and heat generation, an effect that is JSP-1 independent.3
References/Citations:
- Cutshall et al. (2005), Rhodanine derivatives as inhibitors of JSP-1; Bioorg. Med. Chem. Lett., 15 3374
- Albayrak et al. (2022), BML-260 promotes the growth of cord blood and mobilized peripheral blood hematopoietic stem and progenitor cells with improved reconstitution ability; J. Cell. Biochem., 123 2009
- Feng et al. (2019), Identification of a rhodamine derivative BML-260 as a potent stimulator of UCP1 expression; Theranostics, 9 3501
Related products
-
AZ3146 | Mps1 kinase inhibitor
From $60.00CAS:1124329-14-1Catalog Number:10-4778Activity:Mps1 kinase inhibitorChemical Name:9-Cyclopentyl-2-[2-methoxy-4-(1-methylpiperidine-4-yl)oxyanilino]-7-methylpurin-8-oneMolecular Weight:452.56Molecular Formula:C24H32N6O3S2Solubility:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to at least 25 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
N-Eicosanoyl serotonin | Neuroprotective
From $50.00Catalog Number:10-3631Activity:NeuroprotectiveChemical Name:Eicosanoyl-5-hydroxytryptamideAlternate Name:Eicosanoyl serotonin, EHTMolecular Weight:470.73Molecular Formula:C30H50N2O2Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 20 mg/ml with warming)Physical Properties:Beige solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase supplied. Protect from air. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
PNU 74654 | Wnt pathway blocker
From $55.00CAS:113906-27-7Catalog Number:10-4519Activity:Wnt pathway blockerChemical Name:2-Phenoxybenzoic acid [(5-methyl-2-furanyl)methylene]hydrazideMolecular Weight:320.35Molecular Formula:C19H16N2O3Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Off-white solidPurity:>98% by TLC
NMR (conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
