BMS-202 | PD-1/PD-L1 inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $85.00 | ||
| 25 mg | $300.00 |
BMS-202 (1675203-84-5) inhibits (IC50 = 18nM) formation of the PD-1/PD-L1 complex via binding to PD-L1 and inducing dimerization.1,2
References/Citations:
1) Zak et al. (2016), Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1); Oncotarget 7 30323
2) Guzik et al. (2017), Small-molecule inhibitors of the programmed cell death -1/programmed cell death -ligand 1(PD-1/PD-L1) interaction via transiently induced protein states and dimerization of PD-L1; J. Med. Chem. 60 5857
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
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BMS-202 (1675203-84-5) inhibits (IC50 = 18nM) formation of the PD-1/PD-L1 complex via binding to PD-L1 and inducing dimerization.1,2
References/Citations:
1) Zak et al. (2016), Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1); Oncotarget 7 30323
2) Guzik et al. (2017), Small-molecule inhibitors of the programmed cell death -1/programmed cell death -ligand 1(PD-1/PD-L1) interaction via transiently induced protein states and dimerization of PD-L1; J. Med. Chem. 60 5857
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