BRD 7116 | Leukemia cancer stem cell inhibitor

CAS:
329059-55-4
Catalog Number:
10-1616
Activity:
Leukemia cancer stem cell inhibitor
Chemical Name:
N,N’-(Sulfonyldi-1,4-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]
Molecular Weight:
496.66
Molecular Formula:
C28H36N2O4S
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 15 mg/ml)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$50.00
25 mg$200.00

BRD 7116 (329059-55-4) inhibits leukemia stem cell (LSC) activity (EC50 = 200 nM). Displays a >100-fold selectivity for LSCs over normal hematopoietic stem cells.1

References/Citations:

1) Hartwell et al. (2013), Niche-based screening identifies small-molecule inhibitors of leukemia stem cells; Nat. Chem. Biol., 9 840

CAS:
329059-55-4
Catalog Number:
10-1616
Activity:
Leukemia cancer stem cell inhibitor
Chemical Name:
N,N’-(Sulfonyldi-1,4-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]
Molecular Weight:
496.66
Molecular Formula:
C28H36N2O4S
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 15 mg/ml)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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