Bromotetramisole, L(-) oxalate | Alkaline phosphatase inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $48.00 | ||
| 25 mg | $120.00 |
Bromotetramisole oxalate (62284-79-1) is a potent alkaline phosphatase inhibitor.1 Strongly activates cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels by inhibiting a membrane associated protein phosphatase.2 Bromotetramisole oxalate inhibits terminal cell division-associated differentiation in murine erythroleukemia cells.3
References/Citations:
1) Kovach et al. (1992), Levamisole potentiation of fluorouracil antiproliferative activity mimicked by orthovanadate, an inhibitor of tyrosine phosphatase; J. Natl. Cancer Inst., 84 515
2) Luo et al. (2000), Role of protein phosphatases in the activation of CTFR (ABCC7) by genistein and bromotetramisole; Am. J. Physiol. Cell Physiol., 279 C108
3) Scher et al. (1998), The phosphatase inhibitors, orthovanadate and levamisole, inhibit induction of erythroid differentiation and abrogate the associated inhibition of glycolysis; Int. J. Oncol., 12 987
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Bromotetramisole oxalate (62284-79-1) is a potent alkaline phosphatase inhibitor.1 Strongly activates cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels by inhibiting a membrane associated protein phosphatase.2 Bromotetramisole oxalate inhibits terminal cell division-associated differentiation in murine erythroleukemia cells.3
References/Citations:
1) Kovach et al. (1992), Levamisole potentiation of fluorouracil antiproliferative activity mimicked by orthovanadate, an inhibitor of tyrosine phosphatase; J. Natl. Cancer Inst., 84 515
2) Luo et al. (2000), Role of protein phosphatases in the activation of CTFR (ABCC7) by genistein and bromotetramisole; Am. J. Physiol. Cell Physiol., 279 C108
3) Scher et al. (1998), The phosphatase inhibitors, orthovanadate and levamisole, inhibit induction of erythroid differentiation and abrogate the associated inhibition of glycolysis; Int. J. Oncol., 12 987
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