Bz-Val-Gly-Arg-AMC | Proteasome substrate
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $30.00 | ||
| 5 mg | $100.00 |
Bz-VGR-AMC (87779-49-5) may be used for measuring the trypsin-like activity of the 20S proteasome, in combination with Suc-LLVY-AMC (Cat.# 10-2971, for assaying its chymotrypsin-like activity) and Z-LLE-AMC, (for determining its PGPH activity). Fluorogenic substrate. Ex.: 380nm Em.: 460nm.
References/Citations:
1) Gillardon et al. (2007), The 20S proteasome isolated from Alzheimer’s disease brain shows post-translational modifications but unchanged proteolytic activity; J. Neurochem., 101 1483
2) Kim et al. (2002), Navigation inside a protease: substrate selection and product exit in tricorn protease from Thermoplasma acidophilum; J. Mol. Biol., 324 1041
3) Dahlmann et al. (2000), Different proteasome subtypes in a single tissue exhibit different enzymatic properties; J. Mol. Biol., 303 643
4) Lightcap et al. (2000), Proteasome inhibition measurements: clinical application; Clin. Chem., 46 673
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Bz-VGR-AMC (87779-49-5) may be used for measuring the trypsin-like activity of the 20S proteasome, in combination with Suc-LLVY-AMC (Cat.# 10-2971, for assaying its chymotrypsin-like activity) and Z-LLE-AMC, (for determining its PGPH activity). Fluorogenic substrate. Ex.: 380nm Em.: 460nm.
References/Citations:
1) Gillardon et al. (2007), The 20S proteasome isolated from Alzheimer’s disease brain shows post-translational modifications but unchanged proteolytic activity; J. Neurochem., 101 1483
2) Kim et al. (2002), Navigation inside a protease: substrate selection and product exit in tricorn protease from Thermoplasma acidophilum; J. Mol. Biol., 324 1041
3) Dahlmann et al. (2000), Different proteasome subtypes in a single tissue exhibit different enzymatic properties; J. Mol. Biol., 303 643
4) Lightcap et al. (2000), Proteasome inhibition measurements: clinical application; Clin. Chem., 46 673
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