C2-Dihydroceramide | Autophagy inducer

CAS:
13031-64-6
Catalog Number:
10-1381
Activity:
Autophagy inducer
Chemical Name:
N-Acetyl-D-erythro-sphinganine
Molecular Weight:
343.54
Molecular Formula:
C20H41NO3
Solubility:
Soluble in DMSO (up to 5 mg/ml, with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$60.00
25 mg$240.00

C2 Dihydroceramide (13031-64-6) is a negative control for C2-ceramide (cat.# 10-1181).1,2 Induces autophagy in a variety of cell types.3,4

References/Citations:

1) Bielawska et al. (1993) Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide; J. Biol. Chem. 268 26226
2) Obeid et al. (1993) Programmed cell death induced by ceramide; Science, 259 1769
3) Jiang et al. (2012) Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide; Int. J. Cancer, 130 685
4) Siddique et al. (2015) Dihydroceramides: From Bit Players to Lead Actors; J. Biol. Chem., 290 15371

CAS:
13031-64-6
Catalog Number:
10-1381
Activity:
Autophagy inducer
Chemical Name:
N-Acetyl-D-erythro-sphinganine
Molecular Weight:
343.54
Molecular Formula:
C20H41NO3
Solubility:
Soluble in DMSO (up to 5 mg/ml, with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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