Caerulomycin A | Blocks STAT1 signaling / Immunosuppressant
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 100 µg | $80.00 | ||
| 1 mg | $312.00 |
Caerulomycin A (21802-37-9) chemically novel and potent immunosuppressive agent. Suppresses T cell activation and IFN7gamma; secretion in vitro and in vivo.1 Caerulomycin A induces expansion of regulatory T cells by via interfering with IFNγ -induced STAT1 signaling.2
References/Citations:
1) Singla et al. (2014), Caerulomycin A suppresses immunity by inhibiting T cell activity; PLoS One, 9(10) e107051
2) Gurram et al. (2014), Caerulomycin A enhances transforming growth factor-beta (TGF-β)-Smad3 protein signaling by suppressing interferon-gamma (IFN-γ)-signaling to expand regulatory T cells (Tregs); J. Biol. Chem. 289 17515
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
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Caerulomycin A (21802-37-9) chemically novel and potent immunosuppressive agent. Suppresses T cell activation and IFN7gamma; secretion in vitro and in vivo.1 Caerulomycin A induces expansion of regulatory T cells by via interfering with IFNγ -induced STAT1 signaling.2
References/Citations:
1) Singla et al. (2014), Caerulomycin A suppresses immunity by inhibiting T cell activity; PLoS One, 9(10) e107051
2) Gurram et al. (2014), Caerulomycin A enhances transforming growth factor-beta (TGF-β)-Smad3 protein signaling by suppressing interferon-gamma (IFN-γ)-signaling to expand regulatory T cells (Tregs); J. Biol. Chem. 289 17515
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