Caerulomycin A | Blocks STAT1 signaling / Immunosuppressant
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 100 µg | $80.00 | ||
| 1 mg | $312.00 |
Caerulomycin A (21802-37-9) chemically novel and potent immunosuppressive agent. Suppresses T cell activation and IFN7gamma; secretion in vitro and in vivo.1 Caerulomycin A induces expansion of regulatory T cells by via interfering with IFNγ -induced STAT1 signaling.2
References/Citations:
1) Singla et al. (2014), Caerulomycin A suppresses immunity by inhibiting T cell activity; PLoS One, 9(10) e107051
2) Gurram et al. (2014), Caerulomycin A enhances transforming growth factor-beta (TGF-β)-Smad3 protein signaling by suppressing interferon-gamma (IFN-γ)-signaling to expand regulatory T cells (Tregs); J. Biol. Chem. 289 17515
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Caerulomycin A (21802-37-9) chemically novel and potent immunosuppressive agent. Suppresses T cell activation and IFN7gamma; secretion in vitro and in vivo.1 Caerulomycin A induces expansion of regulatory T cells by via interfering with IFNγ -induced STAT1 signaling.2
References/Citations:
1) Singla et al. (2014), Caerulomycin A suppresses immunity by inhibiting T cell activity; PLoS One, 9(10) e107051
2) Gurram et al. (2014), Caerulomycin A enhances transforming growth factor-beta (TGF-β)-Smad3 protein signaling by suppressing interferon-gamma (IFN-γ)-signaling to expand regulatory T cells (Tregs); J. Biol. Chem. 289 17515
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