Capsaicin (natural) | TRPV1 activator
NOTE: product is a mixture of capsaicin and dihydrocapsaicin which are unresolvable by TLC.
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 200 mg | $80.00 | ||
| 1 gram | $250.00 |
Capsaicin (404-86-4) is a vanilloid agonist known to activate the transient receptor potential channel vanilloid subfamily member 1 (TRPV1)1,2 and to possess analgesic3, anti-inflammatory4 and hypolocomotor effects5.
SEVERE IRRITANT – HANDLE WITH CARE
References/Citations:
1) Gunthorpe et al. (2002) The diversity in the vanilloid (TRPV) receptor family of ion channels; Trends Pharmacol. Sci. 23 183
2) Van Der Stelt and Di Marzo (2004) Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels; Eur. J. Biochem. 271 1827
3) Perkins and Campbell (1992) Capsazepine reversal of the antinociceptive action of capsaicin in vivo; Br. J. Pharmacol. 107 329
4) Kim et al..(2003) Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages; Cell. Signal., 15 299
5) Di Marzo et al. (2001) Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues; Eur. J. Pharmacol., 420 123
NOTE: product is a mixture of capsaicin and dihydrocapsaicin which are unresolvable by TLC.
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Capsaicin (404-86-4) is a vanilloid agonist known to activate the transient receptor potential channel vanilloid subfamily member 1 (TRPV1)1,2 and to possess analgesic3, anti-inflammatory4 and hypolocomotor effects5.
SEVERE IRRITANT – HANDLE WITH CARE
References/Citations:
1) Gunthorpe et al. (2002) The diversity in the vanilloid (TRPV) receptor family of ion channels; Trends Pharmacol. Sci. 23 183
2) Van Der Stelt and Di Marzo (2004) Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels; Eur. J. Biochem. 271 1827
3) Perkins and Campbell (1992) Capsazepine reversal of the antinociceptive action of capsaicin in vivo; Br. J. Pharmacol. 107 329
4) Kim et al..(2003) Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages; Cell. Signal., 15 299
5) Di Marzo et al. (2001) Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues; Eur. J. Pharmacol., 420 123
Related products
-
SC-514 | IKK-2 inhibitor
From $65.00CAS:354812-17-2Catalog Number:10-1054Activity:IKK-2 inhibitorChemical Name:5-(Thien-3-yl)-3-aminothiophene-2-carboxamideMolecular Weight:224.3Molecular Formula:C9H8N2OS2Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
ISO-1 | MIF antagonist
From $60.00CAS:478336-92-4Catalog Number:10-1185Activity:MIF antagonistChemical Name:(S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl esterMolecular Weight:235.24Molecular Formula:C12H13NO4Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
AS-041164 | PI3Kgamma inhibitor
From $54.00CAS:6318-41-8Catalog Number:10-1035Activity:PI3Kγ inhibitorChemical Name:5-(1,3-Benzodioxol-5-yl)methylidene-1,3-thiazolidine-2,4-dioneMolecular Weight:249.24Molecular Formula:C11H7NO4SSolubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by TLCStorage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
