Cardamonin | NFkB inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $60.00 | ||
| 25 mg | $240.00 |
Cardamonin (19309-14-9) inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear translocation.1,2 Cardamonin displays anti-inflammatory activity in various models.3 Cell permeable.
References/Citations:
1) Lee et al. (2006), Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamonin, a chalcone analog from Alpinia conchigera; J. Pharmacol. Exp. Ther., 316 271
2) Israf et al. (2007), Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB nuclear translocation and Ikappa-B phosphorylation in RAW 264.7 macrophage cells; Mol. Immunol., 44 673
3) Ahmad et al. (2006), Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood; Eur. Pharmacol. Exp. Ther., 538 188
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
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Cardamonin (19309-14-9) inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear translocation.1,2 Cardamonin displays anti-inflammatory activity in various models.3 Cell permeable.
References/Citations:
1) Lee et al. (2006), Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamonin, a chalcone analog from Alpinia conchigera; J. Pharmacol. Exp. Ther., 316 271
2) Israf et al. (2007), Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB nuclear translocation and Ikappa-B phosphorylation in RAW 264.7 macrophage cells; Mol. Immunol., 44 673
3) Ahmad et al. (2006), Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood; Eur. Pharmacol. Exp. Ther., 538 188
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