CDD-2789 | ALK1/2 inhibitor

CAS:
 3052084-77-9
Catalog Number:
 10-4451
CDD-2789 chemical structure

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5 mg$75.00
25 mg$265.00

CDD-2789 (3052084-77-9) is a potent (IC50 = 3.9 nM ALK1; 2.1 nM ALK2) and selective ALK1/2 inhibitor. It attenuated activin A and BMP-induced phosphorylated SMAD1/5 activation in fibroblasts in a dose-dependent manner.

  1. Jimidi et al. (2024), Discovery of highly potent and ALK2/ALK1 selective kinase inhibitors using DNA-encoded chemistry technology; Proc. Natl. Acad. Sci. USA 121 e2413108121
CAS:
3052084-77-9
Catalog Number:
10-4451
Activity:
ALK1/2 inhibitor
Chemical Names:
1-Cyclobutyl-N-(3-(dimethylamino)propyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazole-6-carboxamide
Molecular Weight:
466.58
Molecular Formula:

C26H34N4O4

Solubility:
Soluble in DMSO (at least 60 mg/ml)
Physical Properties:
White solid
Purity:

>98% HPLC
NMR: (Conforms)

Storage Temperature:
-20°C
Stability:
Stable for up to 2 years when stored as supplied @ -20°C. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

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