Chaetocin | Lys methyltransferase inhibitor

CAS:
28097-03-2
Catalog Number:
10-2404
Activity:
Lys methyltransferase inhibitor
Chemical Name:
Isolated from Chaetomium species
Molecular Weight:
696.85
Molecular Formula:
C30H28N6O6S4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98%
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
200 µg$50.00
1 mg$190.00

Chaetocin (28097-69-1) is an antimicrobial fungal metabolite. Selective inhibitor of lysine specific histone methytransferase.1 Chaetocin has an antimyeloma activity which has been linked to induction of oxidative stress and subsequent apoptosis.2

References/Citations:

1) Greiner et al. (2005), Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9; Nat. Chem. Biol., 1 143
2) Isham et al. (2007), Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress; Blood, 109 2579

CAS:
28097-03-2
Catalog Number:
10-2404
Activity:
Lys methyltransferase inhibitor
Chemical Name:
Isolated from Chaetomium species
Molecular Weight:
696.85
Molecular Formula:
C30H28N6O6S4
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98%
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

20% OFF

For Postdoc
Customers!