CID-2011756 | PKD inhibitor

CAS:
638156-11-3
Catalog Number:
10-1420
Activity:
PKD inhibitor
Chemical Name:
5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide
Molecular Weight:
396.88
Molecular Formula:
C22H21ClN2O3
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 8 mg/ml with warming).
Physical Properties:
Tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$60.00
25 mg$240.00

CID-2011756 (638156-11-3) is a potent and selective ATP-competitive inhibitor of protein kinase D (PKD). IC50=3.2, 0.6 and 0.7 μM for PKD1, 2 and 3 respectively. Inhibits phorbol ester-induced PKD activation in LNCaP prostate cancer cells. Cell permeable.

References/Citations:

1) Sharlow et al. (2011), Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity; PLoS One, 6 e25134

CAS:
638156-11-3
Catalog Number:
10-1420
Activity:
PKD inhibitor
Chemical Name:
5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide
Molecular Weight:
396.88
Molecular Formula:
C22H21ClN2O3
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 8 mg/ml with warming).
Physical Properties:
Tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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