2-[[(Benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid; ML282
Size: | Price | Quantity | |
---|---|---|---|
5 mg | $65.00 | ||
25 mg | $240.00 |
CID1067700 (314042-01-8) is a specific competitive inhibitor of nucleotide binding to Rab7, an endosome-localized small GTPase.1 It interferes with the Rab7-RILP interaction, locking the GTPase in an inactive conformation.2 Impairs B cell class switching and plasma cell survival dampening, the pathogenic autoantibody response in lupus.3 Inhibits the Arf-like small GTPase Arl8b, blocking cellular egress of ß-coronaviruses (SARS-CoV-2) which utilize a lysosomal exocytosis pathway.4
References/Citations:
2-[[(Benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid; ML282
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CID1067700 (314042-01-8) is a specific competitive inhibitor of nucleotide binding to Rab7, an endosome-localized small GTPase.1 It interferes with the Rab7-RILP interaction, locking the GTPase in an inactive conformation.2 Impairs B cell class switching and plasma cell survival dampening, the pathogenic autoantibody response in lupus.3 Inhibits the Arf-like small GTPase Arl8b, blocking cellular egress of ß-coronaviruses (SARS-CoV-2) which utilize a lysosomal exocytosis pathway.4
References/Citations:
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