Size | Price | Quantity | |
---|---|---|---|
5mg | $100.00 | ||
25mg | $350.00 |
CPI203 (1446144-04-2), a JQ1 analog, is a potent and selective inhibitor of the BET bromodomain BRD4 (IC50 = 26 nM).1 It helps promote the maintenance of hematopoietic stem cells via repression of Myc expression.2 CPI203 reversibly suppressed intestinal stem cell differentiation in a mouse model.3 It enhanced the expansion of human cord blood hematopoietic stem cells without losing cell viability.4 CPI203 displays synergistic antitumor activity with various agents including lenalidomide5, bortezomib6, and PARP inhibitors7.
Refences/Citations:
C19H18ClN5OS
>98% HPLC
NMR (Conforms)
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CPI203 (1446144-04-2), a JQ1 analog, is a potent and selective inhibitor of the BET bromodomain BRD4 (IC50 = 26 nM).1 It helps promote the maintenance of hematopoietic stem cells via repression of Myc expression.2 CPI203 reversibly suppressed intestinal stem cell differentiation in a mouse model.3 It enhanced the expansion of human cord blood hematopoietic stem cells without losing cell viability.4 CPI203 displays synergistic antitumor activity with various agents including lenalidomide5, bortezomib6, and PARP inhibitors7.
Refences/Citations:
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Concentration × Volume × Molecular Weight = Mass
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