CVPA | Aquaporin 1 inhibitor

CAS:
37710-81-9
Catalog Number:
10-1430
Activity:
Aquaporin 1 inhibitor
Alternate Names:
3,3′-(1,3-Phenylene)bis(2-propenoic acid)
Chemical Name:
3-[3-(2-Carboxy-vinyl)-phenyl]-acrylic acid
Molecular Weight:
218.21
Molecular Formula:
C12H10O4
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
97% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
10 mg$60.00
50 mg$240.00

CVPA (37710-81-9) is an aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.1

References/Citations:

1) Seeliger et al. (2012), Discovery of novel human aquaporin-1 blockers; ACS Chem. Biol., 8 249

CAS:
37710-81-9
Catalog Number:
10-1430
Activity:
Aquaporin 1 inhibitor
Alternate Names:
3,3′-(1,3-Phenylene)bis(2-propenoic acid)
Chemical Name:
3-[3-(2-Carboxy-vinyl)-phenyl]-acrylic acid
Molecular Weight:
218.21
Molecular Formula:
C12H10O4
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
97% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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